Rectal aspirin--absorption and antipyretic effect.

Rectal aspirin--absorption and antipyretic effect.

Rectal acetylsalicylic acid was given to 14 children who had undergone open heart surgery. The effect on their temperatures was similar whether 15--30 or 30--50 mg/kg was given. Either dose was more effective than no treatment. The greatest fall in temperature occurred after 4 or 5 hours. Rectal aspirin in a triglyceride base is effective in lowering postoperative temperature. It should also be...

Analgesic, Antipyretic and Anti-Inflammatory Effects of Aspirin in

The reason of this study was to evaluate the action of oxidative stress (OS) induced with hydrogen peroxide (H2O2) on the analgesic, antipyretic and anti-inflammatory effects of aspirin in 7-14 day old chicks. H2O2 at 0.5 % v/v in drinking water induced OS in age 7-14 of the chicks when given freshly. The analgesic Median Effective Dose (ED50) and acute Median Lethal Dose (LD50) values of aspir...

Re : " Equal antipyretic efficacy of oral and rectal acetaminophen : a

Equal antipyretic effectiveness of oral and rectal acetaminophen: a randomized controlled trial Title: [ISRCTN11886401]

Antipyretic effect of ketoprofen.

OBJECTIVE The aim of this study was to investigate the efficacy and side effect profile of ketoprofen as well as compliance with respect to the taste of the drug and compare these parameters with those of acetaminophen and ibuprofen. METHODS A total of 301 patients between 1-14 years of age who applied to emergency rooms of three medical centers with the complaint of fever that required antip...

Equal antipyretic effectiveness of oral and rectal acetaminophen : a